Adipose Stem Cell Therapy For Knees

Mscs can be isolated from adipose tissue bone marrow synovial tissue and other sources the excitement surrounding research on stem cell therapy for osteoarthritis centers on the possibility of stem cell therapy reducing the need for joint replacement as primary care for diseased joint.

Adipose stem cell therapy for knees.

Adipose derived stem cell treatment for osteoarthritic knees overview jay smith m d vice chair of physical medicine and rehabilitation at mayo clinic describes a clinical trial to evaluate the safety and efficacy of adipose derived mesenchymal stromal cell injections as a treatment for patients with osteoarthritic knees. This is a randomized double blind placebo controlled trial in 90 patients evaluating the efficacy and safety of adrc s autologous adipose stem cell therapy. Stem cell treatment for knees is noninvasive and studies suggest that side effects are minimal. Human adipose derived mesenchymal progenitor cells hampcs are stem cells with multiple differentiation potential and immunomodulatory function.

In this light we have started a clinical trial that utilizes the stem cells found in patients fat adipose tissue separate them out and re inject them into the joint that same day. The condition that berman s clinics treat most often is knee pain and stem cell therapies may someday become the first line of treatment for patients with mild knee arthritis says philipp. A phase i dose escalation trial stem cells transl med. It provides us with donor mesenchymal stem cells which we mix with recycled autologous cells to quickly obtain enough cells to fill the patient s cartilage defect without operating twice says daniel b.

Re join comprises in vitro expanded hampcs from adipose tissue of patients combined with cell suspension solution. For knee injections doctors often take stem cells from the patient s bone marrow fat tissue or blood. This study was undertaken to evaluate the efficacy and safety of re join in patients with symptomatic knee osteoarthritis oa. Adipose mesenchymal stromal cell based therapy for severe osteoarthritis of the knee.

After the procedure some people may experience temporary increased pain and swelling. Mayo is unique in having an adipose derived allogeneic stem cell bank.